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Vitamin

Vitamin B12

Essential vitamin for energy metabolism and nervous system function.

Capsule, Tablet, Sublingual, Liquid|Energy|From $0.10/serve

How it works

Mechanism of Action

B12 is required for mitochondrial energy production, DNA synthesis, and the formation of red blood cells that carry oxygen.

Evidence-based uses

What Vitamin B12 Is Used For

Energy

Methylcobalamin form is preferred. Especially important for vegetarians/vegans.

Strong
500-1000mcg/day
Take in the morning
2-4 weeks

Clinical Evidence

Vitamin B12 supplementation and fatigue in adults with low-normal levels (2020)systematic_review · n=1500

Systematic review found B12 supplementation significantly reduced fatigue in deficient individuals, with improvements in energy and cognitive function within 2-4 weeks of treatment.

Safety

Interactions & Warnings

Metforminmoderate · drug

Metformin reduces vitamin B12 absorption over time. If you take metformin, regular B12 monitoring is recommended — supplementation may be necessary.

Proton pump inhibitors (PPIs)moderate · drug

Long-term PPI use (omeprazole, pantoprazole) reduces stomach acid needed for B12 absorption. Consider sublingual or injection forms.

Compare prices

Buy Vitamin B12 in Australia

6 products compared across Australian retailers. Sorted by price per serve.

ProductPrice/serve
Best

NOW Foods

Methyl B-12 1000 mcg, 100 Lozenges

iHerb

$9.99$0.10Buy

Blackmores

Mega B Complex 200 Tablets

Chemist Warehouse

$24.99$0.13Buy

Blackmores

Blackmores Mega B12 1000mcg

Chemist Warehouse

$19.99$0.27Buy

Herbs of Gold

Activated B12 75 Tablets

Mr Vitamins

$26.95$0.36Buy

Thorne

Thorne Methylcobalamin

Thorne

$28.00$0.47Buy

Thorne

Methylcobalamin 60 Capsules

Thorne

$29.99$0.50Buy

Prices in AUD. Some links are affiliate links — we may earn a commission at no extra cost to you.

Should you take Vitamin B12?

Get a personalised supplement stack based on your health goals, age, medications, and preferences.

This information is for educational purposes only and is not intended as medical advice. Always consult a healthcare professional before starting any supplement. Evidence ratings are based on peer-reviewed clinical research. Individual results may vary.