Glycine
Simplest amino acid with wide-ranging benefits for sleep, collagen synthesis, and cognitive function. Excellent safety profile even at high doses.
How it works
Mechanism of Action
Acts as an inhibitory neurotransmitter promoting relaxation. Essential building block for collagen (33% of collagen is glycine). Supports glutathione synthesis and bile acid conjugation.
Evidence-based uses
What Glycine Is Used For
Lowers core body temperature and acts on NMDA receptors to promote sleep. Very safe even at high doses. May improve sleep quality without next-day grogginess.
Clinical Evidence
Glycine 3g before bed improved subjective sleep quality, reduced sleep latency, and decreased daytime sleepiness. Mechanism involves lowering core body temperature via peripheral vasodilation.
Subjects taking 3g glycine before bed reported significantly improved sleep satisfaction, reduced daytime drowsiness, and improved cognitive function next day.
Essential building block of collagen (every third amino acid). Supplementing supports endogenous collagen synthesis.
Clinical Evidence
Glycine as a collagen precursor (every 3rd amino acid in collagen) supports wound healing and skin repair when supplemented alongside vitamin C.
Compare prices
Buy Glycine in Australia
5 products compared across Australian retailers. Sorted by price per serve.
| Product | Price | /serve | |
|---|---|---|---|
Best BulkSupplements BulkSupplements Glycine Powder BulkSupplements | $18.90 | $0.06 | Buy |
Thorne Thorne Glycine Thorne | $28.00 | $0.11 | Buy |
Life Extension Life Extension Glycine 1000mg Life Extension | $12.00 | $0.12 | Buy |
NOW Foods NOW Glycine 1000mg iHerb | $12.90 | $0.13 | Buy |
Source Naturals Source Naturals Glycine Powder Amazon AU | $22.50 | $0.14 | Buy |
Prices in AUD. Some links are affiliate links — we may earn a commission at no extra cost to you.
Should you take Glycine?
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This information is for educational purposes only and is not intended as medical advice. Always consult a healthcare professional before starting any supplement. Evidence ratings are based on peer-reviewed clinical research. Individual results may vary.