Essential mineral involved in 300+ enzymatic reactions including sleep regulation and stress response.
How it works
Magnesium activates the parasympathetic nervous system, regulates GABA receptors, and helps regulate melatonin production.
Evidence-based uses
Magnesium glycinate or threonate forms are preferred for sleep.
Clinical Evidence
Magnesium supplementation resulted in significant increases in sleep time, sleep efficiency, and melatonin concentration, with significant decreases in insomnia severity.
Supplementation with 500mg magnesium daily for 8 weeks significantly improved subjective insomnia measures (ISI), sleep time, sleep efficiency, and melatonin concentration.
Magnesium glycinate is preferred for calming effects.
Clinical Evidence
Systematic review of 18 studies found magnesium supplementation (200-400mg/day) reduced subjective measures of anxiety, with strongest effects in those with mild-to-moderate anxiety and low baseline magnesium.
Safety
Magnesium may enhance the blood pressure-lowering effect of antihypertensive medications.
Magnesium can reduce absorption of bisphosphonates. Take at least 2 hours apart.
Magnesium can bind to certain antibiotics and reduce their absorption. Take at least 2 hours apart.
Compare prices
6 products compared across Australian retailers. Sorted by price per serve.
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| Product | Price | /serve | |
|---|---|---|---|
Best BulkSupplements Magnesium Glycinate 250g BulkSupplements | $24.99 | $0.10 | |
Life Extension Magnesium Caps 500mg, 100 Capsules Life Extension | $18.99 | $0.19 | |
NOW Foods Magnesium Glycinate 200 mg, 180 Tablets iHerb | $36.51 | $0.41 | |
Life Extension Life Extension Neuro-Mag L-Threonate Life Extension | $42.00 | $0.47 | |
Garden of Life Garden of Life Whole Food Magnesium Garden of Life | $32.50 | $0.54 | |
Thorne Magnesium Bisglycinate 200mg, 60 Capsules Thorne | $39.99 | $0.67 |
Prices in AUD. Some links are affiliate links — we may earn a commission at no extra cost to you.
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Head to head
Get a personalised dosage recommendation based on your age, weight, and health goals
Magnesium has 3 known interactions. Check if it's safe with your medications.
Evidence Lab
A deep dive into the clinical evidence behind magnesium supplementation for insomnia and sleep quality — including which forms work best.
Read article 🧘Both are popular for stress relief — but which has stronger clinical support? We compare the evidence, dosages, and mechanisms.
Read article 🌙Magnesium glycinate, L-theanine, ashwagandha, glycine and apigenin — ranked by clinical evidence. Melatonin is prescription-only in AU, so these are the best OTC options.
Read articlePrice drops, new products, and research updates for magnesium supplements. One email per week, unsubscribe anytime.
This information is for educational purposes only and is not intended as medical advice. Always consult a healthcare professional before starting any supplement. Evidence ratings are based on peer-reviewed clinical research. Individual results may vary.