Melatonin
Natural sleep hormone that regulates circadian rhythm.
How it works
Mechanism of Action
Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, signalling the body to prepare for sleep.
Evidence-based uses
What Melatonin Is Used For
Start with lowest effective dose. Best for jet lag and shift work.
Clinical Evidence
Meta-analysis of 19 studies found melatonin significantly reduced sleep onset latency by 7.06 minutes and increased total sleep time by 8.25 minutes.
Safety
Interactions & Warnings
Melatonin may stimulate immune function, potentially counteracting immunosuppressive therapy.
Melatonin may increase the risk of bleeding when taken with anticoagulants.
Compare prices
Buy Melatonin in Australia
6 products compared across Australian retailers. Sorted by price per serve.
| Product | Price | /serve | |
|---|---|---|---|
Best NOW Foods Melatonin 3 mg, 180 Capsules iHerb | $9.99 | $0.06 | Buy |
NOW Foods NOW Melatonin 3mg iHerb | $14.50 | $0.08 | Buy |
Natrol Melatonin Fast Dissolve 5mg, 150 Tablets Amazon AU | $15.99 | $0.11 | Buy |
Life Extension Melatonin 3mg 60 Capsules Life Extension | $9.99 | $0.17 | Buy |
Life Extension Life Extension Melatonin 3mg Life Extension | $16.50 | $0.28 | Buy |
Thorne Thorne Melaton-3 Thorne | $32.00 | $0.53 | Buy |
Prices in AUD. Some links are affiliate links — we may earn a commission at no extra cost to you.
Should you take Melatonin?
Get a personalised supplement stack based on your health goals, age, medications, and preferences.
This information is for educational purposes only and is not intended as medical advice. Always consult a healthcare professional before starting any supplement. Evidence ratings are based on peer-reviewed clinical research. Individual results may vary.