Natural sleep hormone that regulates circadian rhythm.
How it works
Melatonin binds to MT1 and MT2 receptors in the suprachiasmatic nucleus, signalling the body to prepare for sleep.
Evidence-based uses
Start with lowest effective dose. Best for jet lag and shift work.
Clinical Evidence
Meta-analysis of 19 studies found melatonin significantly reduced sleep onset latency by 7.06 minutes and increased total sleep time by 8.25 minutes.
Safety
Melatonin may stimulate immune function, potentially counteracting immunosuppressive therapy.
Melatonin may increase the risk of bleeding when taken with anticoagulants.
Compare prices
5 products compared across Australian retailers. Sorted by price per serve.
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| Product | Price | /serve | |
|---|---|---|---|
Best NOW Foods Melatonin 3 mg, 180 Capsules iHerb | $9.99 | $0.06 | |
NOW Foods NOW Melatonin 3mg iHerb | $14.50 | $0.08 | |
Life Extension Melatonin 3mg 60 Capsules Life Extension | $9.99 | $0.17 | |
Life Extension Life Extension Melatonin 3mg Life Extension | $16.50 | $0.28 | |
Thorne Thorne Melaton-3 Thorne | $32.00 | $0.53 |
Prices in AUD. Some links are affiliate links — we may earn a commission at no extra cost to you.
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Also consider
Mineral
Essential mineral involved in 300+ enzymatic reactions including sleep regulation and stress response.
Amino Acid
Amino acid found in tea that promotes relaxation without drowsiness.
Herb
Traditional herbal remedy used for centuries to promote sleep.
Amino Acid
Simplest amino acid with wide-ranging benefits for sleep, collagen synthesis, and cognitive function. Excellent safety profile even at high doses.
Head to head
Melatonin has 2 known interactions. Check if it's safe with your medications.
Evidence Lab
Magnesium glycinate, L-theanine, ashwagandha, glycine and apigenin — ranked by clinical evidence. Melatonin is prescription-only in AU, so these are the best OTC options.
Read article 🔬An honest, evidence-based look at whether magnesium, L-theanine, valerian, glycine, and melatonin actually improve sleep — and what Australian sleep researchers think.
Read articlePrice drops, new products, and research updates for melatonin supplements. One email per week, unsubscribe anytime.
This information is for educational purposes only and is not intended as medical advice. Always consult a healthcare professional before starting any supplement. Evidence ratings are based on peer-reviewed clinical research. Individual results may vary.