NAC (N-Acetyl Cysteine)
Precursor to glutathione, the body's most powerful antioxidant. Supports liver detoxification, respiratory health, and mental health.
How it works
Mechanism of Action
Provides cysteine for glutathione synthesis. Modulates glutamate neurotransmission. Reduces oxidative stress and inflammation. Thins mucus in respiratory conditions.
Evidence-based uses
What NAC (N-Acetyl Cysteine) Is Used For
Supports glutathione production, the body's master antioxidant. Well-studied for respiratory health and immune support.
Clinical Evidence
NAC 600mg 2x/day for 6 months significantly reduced influenza episodes and severity. Only 25% of infected NAC subjects were symptomatic vs 79% placebo.
Modulates glutamate, which may help with OCD, anxiety, and addictive behaviors. Growing evidence base.
Clinical Evidence
NAC shows promise across multiple psychiatric conditions including OCD, depression, bipolar disorder, and addiction through glutamate modulation and oxidative stress reduction.
Safety
Interactions & Warnings
NAC enhances the vasodilatory effects of nitroglycerin, potentially causing severe headache and dangerous blood pressure drops.
Charcoal may absorb NAC, reducing its effectiveness. Separate doses by at least 2 hours.
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Should you take NAC (N-Acetyl Cysteine)?
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This information is for educational purposes only and is not intended as medical advice. Always consult a healthcare professional before starting any supplement. Evidence ratings are based on peer-reviewed clinical research. Individual results may vary.