A strong immune system is your first line of defence. These evidence-backed supplements may help support immune function, especially during winter months.
Add your age, medications, and preferences for a tailored recommendation with prices compared across 10+ retailers.
Research highlights
Ranked by evidence strength and effectiveness. Get personalised dosages above.
May reduce cold duration. Higher doses during illness may help.
Most Australians are deficient in winter. Get levels tested. Maintain 75-100 nmol/L.
Zinc lozenges within 24 hours of cold onset may reduce duration.
May reduce cold and flu duration and severity. Not for autoimmune conditions.
Supports glutathione production, the body's master antioxidant. Well-studied for respiratory health and immune support.
Natural antihistamine and zinc ionophore. Pairs well with zinc for immune support. May reduce allergy symptoms.
Lion's Mane contains beta-glucans that stimulate innate immune function. Animal and in vitro studies show enhanced macrophage and NK cell activity. The polysaccharides in the fruiting body have demonstrated immunomodulating properties. Human clinical evidence is limited but mechanistic support is strong.
Evidence ratings based on peer-reviewed clinical research. Individual results may vary.
Our recommendations are based on peer-reviewed clinical research. We evaluate each supplement on effectiveness, evidence quality, safety profile, and value for money across Australian retailers.
Always consult a healthcare professional before starting any supplement regimen, especially if you are taking medications or have existing health conditions.
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Common questions
Based on clinical research, the top supplements for immunity include Vitamin C, Vitamin D, Zinc. The best choice depends on your individual circumstances. SuppUp analyses evidence and compares prices across Australian retailers.
SuppUp compares prices across 10+ Australian-shipping retailers including iHerb, Chemist Warehouse, Mr Vitamins, Thorne, and more to find the best deal for each supplement.
Most supplements take 2–12 weeks to show noticeable effects, depending on the specific supplement and individual factors. SuppUp provides specific timelines for each recommendation.
Some supplements for immunity can interact with medications. SuppUp checks for drug interactions automatically when you mention your medications. Always consult your GP or pharmacist before combining supplements with prescription drugs.
SuppUp evaluates supplements based on four evidence levels: Strong (multiple RCTs or meta-analyses), Moderate (clinical trials with promising results), Preliminary (early research), and Traditional (long history of use). Rankings also consider safety, cost-effectiveness, and bioavailability.
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Evidence Lab
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